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Single Covid vaccine dose in Israel 'less effective than we thought'

https://www.theguardian.com/world/2021/jan/19/single-covid-vaccine-dose-in-israel-less-effective-than-we-hoped

Israel’s coronavirus tsar has warned that a single dose of the Pfizer/BioNTech vaccine may be providing less protection than originally hoped, as the country reported a record 10,000 new Covid infections on Monday.

In remarks reported by Army Radio, Nachman Ash said a single dose appeared “less effective than we had thought”, and also lower than Pfizer had suggested.

By contrast, those who had received their second dose of the Pfizer vaccine had a six- to 12-fold increase in antibodies, according to data released by Sheba Medical Center in Tel Hashomer on Monday.

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Op-ED: How to Distribute 100 Million Vaccine Doses in 100 Days

Faced with a slow, chaotic vaccine rollout and ever-rising Covid-19 cases, President Biden has an ambitious plan: to administer 100 million doses of the coronavirus vaccine in his first 100 days in office. Since the vaccines became publicly available in mid-December, 16.5 million shots have made their way into the arms of Americans, an average of 447,000 doses per day. Mr. Biden’s goal of more than doubling this rate can be achieved if the United States implements a vaccination campaign that treats Covid-19 more like an act of bioterrorism and less like the seasonal flu.

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New California Variant May Be Driving Virus Surge There, Study Suggests

In late December, scientists in California began searching coronavirus samples for a fast-spreading new variant that had just been identified in Britain.

They found it, though in relatively few samples. But in the process, the scientists made another unwelcome discovery: California had produced a variant of its own.

That mutant, which belongs to a lineage known as CAL.20C, seemed to have popped up in July but lay low till November. Then it began to quickly spread.

CAL.20C accounted for more than half of the virus genome samples collected in Los Angeles laboratories on Jan. 13, according to a new study that has not yet been published.

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Three questions and the emerging answers about COVID-19 Vaccine protection--NPR

As the COVID-19 vaccine rolls out, three big questions loom. First, can someone who has been vaccinated still spread the disease? Second, will the vaccine remain effective as the virus itself evolves? And third, how long will the vaccine's protection last?

Answers to these questions lie in our immune systems. And the answers aren't straightforward because our immune systems are both remarkably adept and remarkably challenging to predict.

...the first question, about whether people who are vaccinated can still spread the disease. Marion Pepper, an immunologist at the University of Washington, says that's not just an open question for this vaccine, but for vaccines in general.

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A Nationwide Mask Mandate Could Add $1 Trillion To The US GDP, According To UCLA Analysis

Implementation of a nationwide mask mandate, combined with complementary public health measures, could reduce the coronavirus’ spread to essentially zero and have a potential $1 trillion impact on the U.S. GDP, according to researchers at UCLA Fielding School of Public Health.

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