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ANALYSIS: Why emergency COVID-vaccine approvals pose a dilemma for scientists

After a flurry of positive results from clinical trials of COVID-19 vaccines, developers are now seeking ‘emergency use’ approvals, which could see these immunizations deployed in potentially tens of millions of people. But scientists are concerned that this kind of early deployment could compromise the ongoing clinical trials that seek to show conclusively how well the vaccines work.

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What the data say about asymptomatic COVID infections

How many people don’t experience any symptoms after becoming infected with SARS-CoV-2? And what is their role in spreading COVID-19? These have been key questions since the beginning of the pandemic.

Now, evidence suggests that about one in five infected people will experience no symptoms, and they will transmit the virus to significantly fewer people than someone with symptoms. But researchers are divided about whether asymptomatic infections are acting as a ‘silent driver’ of the pandemic.

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Health systems are using AI to predict severe Covid-19 cases. But limited data could produce unreliable results

As the United States braces for a bleak winter, hospital systems across the country are ramping up their efforts to develop AI systems to predict how likely their Covid-19 patients are to fall severely ill or even die. Yet most of the efforts are being developed in silos and trained on limited datasets, raising crucial questions about their reliability.

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